Email this article Analisis Rasio Neutrofil Limfosit pada Pasien Carcinoma Mammae dengan Risiko Kejadian Efusi Pleura
Abstract
Kanker payudara merupakan salah satu jenis kanker yang paling sering ditemukan, dengan komplikasi seperti efusi pleura yang dapat memperburuk prognosis pasien. Penelitian ini bertujuan untuk menganalisis hubungan antara rasio neutrofil-limfosit (RNL) dan kejadian efusi pleura pada pasien karsinoma mammae di RSUP Prof Dr. R.D. Kandou Manado. Penelitian ini menggunakan desain potong lintang dengan pendekatan retrospektif, melibatkan 196 pasien kanker payudara, yang terbagi menjadi dua kelompok: pasien dengan dan tanpa efusi pleura. Hasil penelitian menunjukkan bahwa meskipun ada kecenderungan peningkatan RNL pada pasien dengan efusi pleura, faktor-faktor lain seperti stadium kanker dan pembesaran kelenjar getah bening supraklavikula lebih dominan dalam memprediksi efusi pleura. RNL tidak terbukti menjadi biomarker yang kuat untuk memprediksi efusi pleura secara independen. Penelitian ini memberikan wawasan mengenai potensi NLR dalam memprediksi komplikasi pada pasien kanker payudara, namun penelitian lebih lanjut diperlukan untuk mengidentifikasi biomarker yang lebih sensitif dalam memprediksi efusi pleura.
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DOI: https://doi.org/10.32502/sm.v16i1.9839
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